Immunotherapy in Tijuana For Autoimmune Diseases

Immunotherapy for Cancer Treatment in Tijuana

Immunotherapy in Tijuana is at the forefront of treating autoimmune diseases using advanced, personalized approaches. Autoimmune diseases are chronic conditions initiated by an autoimmune response that leads to the destruction of organs due to humoral and cell-mediated immune mechanisms. Each autoimmune disorder is unique in nature, affecting different parts of the body, including:

  • Joints in Rheumatoid Arthritis (RA)
  • Múltiple Sclerosis Psoriasis
  • Diabetes Mellitus (T1D)
  • Skin, kidneys, and serous membranes in Systemic Lupus Erythematosus (SLE)
  • Mucosal cells of the intestine in Inflammatory Bowel Disease (IBD)
  • Hepatic cells in Autoimmune Hepatitis

Other autoimmune conditions like multiple sclerosis (MS), systemic lupus erythematosus, Guillain–Barre syndrome, Crohn’s disease, primary Sjogren syndrome, and psoriasis cause chronic immune responses against host cells, presenting significant challenges for general practitioners and specialists.

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The Role of Regulatory T Cells (Tregs)

types of cells

Regulatory T cells (Tregs) are central to controlling autoimmune responses and minimizing adverse effects from traditional treatments like steroids and chemotherapy. Tregs contribute to immune homeostasis and self-tolerance. With markers Foxp3 and CD4+, Tregs maintain immune balance. Several studies have demonstrated their potential to develop efficient therapeutic regimens for autoimmune disorders and severe allergic reactions. Tregs help:

  • Maintaining Immune Homeostasis: Tregs regulate the immune system to prevent excessive responses that can lead to tissue damage.
  • Promoting Self-Tolerance: They help the immune system recognize and tolerate the body’s own cells and tissues.
  • Reducing Adverse Effects: Minimizing the harmful effects of other autoimmune drugs such as steroids and chemotherapy.

Autoimmune Diseases Treated with Immunotherapy in Tijuana

Rheumatoid Arthritis (RA)

  • Impact on the Body: RA begins in the synovial membrane, which consists of fibroblasts and macrophages. Hyperactivated T and B lymphocytes, endothelial cells, and activated macrophages infiltrate the synovium, causing severe synovial hyperplasia (growth). This leads to bone destruction, inflammation, swelling, pain, and deformity.
  • Treatment: Cellular immunotherapy aims to increase and activate the patient’s own regulatory T-lymphocytes. These Tregs help regulate hyperactivated lymphocytes without destroying them, thus reducing inflammation and joint damage.

Multiple Sclerosis (MS)

  • Disease Mechanism: MS is a chronic autoimmune condition causing inflammation and neurodegeneration in the central nervous system (CNS). It results from immune dysregulation, leading to immune cell infiltration into the CNS, causing demyelination, axonal damage, and neurodegeneration.
  • Potential Triggers: Genetic predisposition, environmental factors (like vitamin D deficiency), and viral infections (such as Epstein-Barr Virus) may trigger MS.
    Treatment: Immunotherapy with Regulatory T lymphocytes helps suppress pro-inflammatory T cells, preventing further neuronal damage and disease progression. Tregs regulate immune responses and protect against autoimmune attacks.
Multiple Sclerosis (MS)

Diabetes Type 1

  • Disease Mechanism: T1D involves the destruction of pancreatic insulin-producing beta cells by the immune system. This autoimmune response is driven by genetic, environmental, and epigenetic factors.
  • Treatment: Immunotherapy extracts, selects, and activates Regulatory T lymphocytes. These Tregs suppress cytotoxic lymphocytes attacking pancreatic cells, preserving insulin production and delaying disease progression.

Psoriasis

  • Disease Context: Psoriasis is a chronic autoimmune and inflammatory disease caused by immune system imbalance. Cytotoxic lymphocytes and inflammatory cytokines like IL-17, IL-34, and INF drive the condition, causing a cycle of activation and chronic tissue damage.
  • Autoantigens Debate: Although psoriasis involves autoinflammation and autoimmunity mechanisms, specific autoantigens remain unidentified.
  • Treatment: Regulatory T lymphocytes deactive cytotoxic lymphocytes, releasing anti-inflammatory cytokines to break the cycle of immune system hyperactivation. Autologous cellular immunotherapy with Tregs has shown effectiveness in properly administered cases.
psoriasis

The Immunotherapy Process in Tijuana

Identification and Separation

The process for immunotherapy in Tijuana begins by identifying and separating relevant immune cells using advanced techniques. Specific markers and methods are used to isolate these cells from the patient’s blood, ensuring precision and accuracy.

Processing and Activation

Isolated immune cells, particularly regulatory T cells, are transported to our cutting-edge laboratory. Here, they undergo detailed analysis and specific activation protocols. This involves preparing the cells to effectively regulate the immune system, tailoring the immunotherapy to the patient’s unique autoimmune profile.

Therapeutic Application

Once activated, the immune cells, particularly Tregs, are introduced back into the patient’s body. These cells work to regulate immune responses, reduce inflammation, and control autoimmune attacks. This process educates the immune system to maintain balance and protect against excessive immune activity that damages healthy tissues.

Ensuring Quality and Safety

Our immunotherapy in Tijuana procedures are conducted in a clean room laboratory, adhering to stringent high standards and safety. All treatment materials are GMP-grade and free from animal-derived proteins, ensuring a 100% autologous treatment with minimal side effects or risk of rejection.

Minimal Side Effects

Patients undergoing immunotherapy in Tijuana typically experience minimal side effects. A small percentage may report mild flu-like symptoms and moderate pain at the injection site. These side effects are generally short-lived and depend on individual pain tolerance.

Advanced Immunotherapy in Tijuana

Immunotherapy in Tijuana offers a breakthrough in treating autoimmune diseases, providing hope and better outcomes for patients globally. Our advanced, personalized treatments harness the body’s immune system to combat chronic conditions effectively.

For more information on how our cutting-edge immunotherapy can help you manage autoimmune diseases and improve your quality of life, contact us or visit our clinic in Tijuana today.